Association of Serum Mannose With Acute Respiratory Distress Syndrome Risk and Survival.

ABSTRACT:

Importance

Acute respiratory distress syndrome (ARDS) confers high mortality risk among critically ill patients. Identification of biomarkers associated with ARDS risk may guide clinical diagnosis and prognosis.

Objective

To systematically evaluate the association of blood metabolites with ARDS risk and survival.

Design, setting, and participants

In this cohort study, data from the Molecular Epidemiology of ARDS (MEARDS) study, a prospective cohort of 403 patients with ARDS and 1227 non-ARDS controls, were analyzed. Patients were recruited in intensive care units (ICUs) at Massachusetts General Hospital and Beth Israel Deaconess Medical Center, both in Boston, Massachusetts, from January 1, 1998, to December 31, 2014. Data analysis was performed from December 9, 2018,

SUBMITTER: Wei Y 

PROVIDER: S-EPMC7841460 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature