M/M/Infinity Birth-Death Processes - A Quantitative Representational Framework to Summarize and Explain Phase Singularity and Wavelet Dynamics in Atrial Fibrillation.

ABSTRACT:

Rationale

A quantitative framework to summarize and explain the quasi-stationary population dynamics of unstable phase singularities (PS) and wavelets in human atrial fibrillation (AF) is at present lacking. Building on recent evidence showing that the formation and destruction of PS and wavelets in AF can be represented as renewal processes, we sought to establish such a quantitative framework, which could also potentially provide insight into the mechanisms of spontaneous AF termination.

Objectives

Here, we hypothesized that the observed number of PS or wavelets in AF could be governed by a common set of renewal rate constants λ _f (for PS or wavelet formation) and λ _d (PS or wavelet destruction), with steady-state population dynamics mod

SUBMITTER: Dharmaprani D 

PROVIDER: S-EPMC7841497 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature