The role of faecal microbiota transplantation: looking beyond <i>Clostridioides difficile</i> infection.

ABSTRACT: Faecal microbiota transplantation (FMT) is the transfer of screened and minimally processed faecal material from a 'healthy' donor to 'diseased' recipient. It has an established role, and is recommended as a therapeutic strategy, in the management of recurrent Clostridioides difficile infection (CDI). Recognition that gut dysbiosis is associated with, and may contribute to, numerous disease states has led to interest in exploiting FMT to 'correct' this microbial imbalance. Conditions for which it is proposed to be beneficial include inflammatory bowel disease, irritable bowel syndrome, liver disease and hepatic encephalopathy, neuropsychiatric conditions such as depression and anxiety, systemic inflammatory states like sepsis, and even coronavirus disease 2019. To understand what ro

SUBMITTER: D Goldenberg S 

PROVIDER: S-EPMC7841662 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature