Significant inverse association of equol-producer status with coronary artery calcification but not dietary isoflavones in healthy Japanese men.

ABSTRACT: Equol, a metabolite of the dietary isoflavone daidzein, is produced by the action of gut bacteria in some individuals who are termed as equol-producers. It is proposed to have stronger atheroprotective properties than dietary isoflavones. We examined a cross-sectional association of dietary isoflavones and equol-producer status with coronary artery calcification (CAC), a biomarker of coronary atherosclerosis, among men in Japan. A population-based sample of 272 Japanese men aged 40-49 years recruited from 2004 to 2007 was examined for serum isoflavones, serum equol, CAC and other factors. Equol-producers were classified as individuals having a serum level of equol >83 nm. The presence of CAC was defined as a coronary Ca score ≥10 Agatston units. The associations of dietary isoflavones and

SUBMITTER: Ahuja V 

PROVIDER: S-EPMC7842214 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature