Learning from scaling up ultra-rapid genomic testing for critically ill children to a national level.

ABSTRACT: In scaling up an ultra-rapid genomics program, we used implementation science principles to design and investigate influences on implementation and identify strategies required for sustainable "real-world" services. Interviews with key professionals revealed the importance of networks and relationship building, leadership, culture, and the relative advantage afforded by ultra-rapid genomics in the care of critically ill children. Although clinical geneticists focused on intervention characteristics and the fit with patient-centered care, intensivists emphasized the importance of access to knowledge, in particular from clinical geneticists. The relative advantage of ultra-rapid genomics and trust in consistent and transparent delivery were significant in creating engagement at initial imple

SUBMITTER: Best S 

PROVIDER: S-EPMC7843635 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature