Acute environmental temperature variation affects brain protein expression, anxiety and explorative behaviour in adult zebrafish.

ABSTRACT: This study investigated the effect of 4-d acute thermal treatments at 18 °C, 26 °C (control) and 34 °C on the nervous system of adult zebrafish (Danio rerio) using a multidisciplinary approach based on behavioural tests and brain proteomic analysis. The behavioural variations induced by thermal treatment were investigated using five different tests, the novel tank diving, light and dark preference, social preference, mirror biting, and Y-Maze tests, which are standard paradigms specifically tailored for zebrafish to assess their anxiety-like behaviour, boldness, social preference, aggressiveness, and explorative behaviour, respectively. Proteomic data revealed that several proteins involved in energy metabolism, messenger RNA translation, protein synthesis, folding and degradation, cytoske

SUBMITTER: Nonnis S 

PROVIDER: S-EPMC7843641 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature