Spexin status in relation to obesity and its related comorbidities: a systematic review.

ABSTRACT:

Purpose

Spexin, a novel 14-amino acid peptide, has multiple physiological functions. The purpose of this paper was to systematically evaluate the current literature on the role of Spexin neuropeptide in obesity and its related comorbidities, food intake and overall metabolic status in human, animal and in vitro studies.

Methods

Multiple databases, including PubMed, EMBASE, ProQuest, Scopus and Google Scholar were searched for English-language papers published since inception until December 2018, that investigated Spexin levels in relation to chronic metabolic diseases, overall metabolism control and feeding-related behaviors.The quality of the included observational studies was assessed by a version of the Newcastle Ottawa Scale (NOS) designed for non-randomized studies and

SUBMITTER: Behrooz M 

PROVIDER: S-EPMC7843752 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature