Body surface area capping may not improve cytotoxic drugs tolerance.

ABSTRACT: Capping body surface area (BSA) at 2 m² is a routine clinical practice. It aims at reducing toxicities in over 2 m² BSA patients. 455,502 computerized chemotherapy prescriptions made between 2011 and 2017 were taken from BPC software. Chemotherapy computerized order entry is created by a senior physician prescribers before patient consultation. Only prescriptions with dose calculation involving BSA were selected. 51,179 chemotherapy prescriptions were analyzed; corresponding to 7206 patients who received intravenous chemotherapy. The number of chemotherapy prescriptions in over 2 m² BSA patients was nearly the same in the hematology as in the oncology departments. But, 79.1% of prescriptions were capped at 2 m² in the oncology department contrary

SUBMITTER: Bouleftour W 

PROVIDER: S-EPMC7843991 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature