Efficacy and Safety of Antiplatelet Agents for Adult Patients With Ischemic Moyamoya Disease.

ABSTRACT: Background: The use of antiplatelet agents in ischemic moyamoya disease (MMD) is controversial. This study aimed to investigate the effectiveness and safety of antiplatelet therapy compared with conservative treatment and surgical revascularization in ischemic MMD patients. Methods: Ischemic MMD patients were retrospectively enrolled from eight clinical sites from January 2013 to December 2018. Follow-up was performed through clinical visits and/or telephone interviews from first discharge to December 2019. The primary outcome was the episodes of further ischemic attacks, and the secondary outcome was the individual functional status. Risk factors for future stroke were identified by the LASSO-Cox regression model. Propensity score matching was applied to assemble a cohort of

SUBMITTER: Ye F 

PROVIDER: S-EPMC7844095 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature