Measuring inter-individual differences in stress sensitivity during MR-guided prostate biopsy.

ABSTRACT: People often experience high level of distress during invasive interventions, which may exceed their coping abilities. This may be in particular evident when confronted with the suspicion of cancer. Taking the example of prostate biopsy sampling, we aimed at investigating the impact of an MRI guided prostate biopsy on the acute stress response and its mechanistic basis. We recruited 20 men with a clinical suspicion of prostate cancer. Immediately before an MRI guided biopsy procedure, we conducted fMRI in the same scanner to assess resting-state brain connectivity. Physiological and hormonal stress measures were taken during the procedure and associated with questionnaires, hair cortisol levels and brain measures to elucidate mechanistic factors for elevated stress. As expected, patients r

SUBMITTER: Kohn N 

PROVIDER: S-EPMC7844251 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature