Effect of mild α-chymotrypsin treatment of highly viscous semen samples on fertilization rates.

ABSTRACT:

Background

Highly viscous semen reduces sperm motility significantly and can contribute to infertility. When processing semen samples, few techniques exist to induce liquefaction in case of seminal hyperviscosity such as different washing steps and mechanical treatment. The use of α-chymotrypsin seems controversial due to possible negative effects on fertilisation rates after in vitro fertilization (IVF). The main objective of this study was to examine the influence of mild α-chymotrypsin treatment of semen samples on the fertilisation rate after artificial reproductive treatment (ART).

Methods

The fertilization rate of 52 ART cycles was examined following IVF using a low dose of α-chymotrypsin to induce liquefaction of highly viscous semen and was compared to a control grou

SUBMITTER: Schallmoser A 

PROVIDER: S-EPMC7844487 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature