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Neutrophil-lymphocyte ratio acts as a novel diagnostic biomarker for kidney stone prevalence and number of stones passed.


ABSTRACT:

Background

This study evaluated the relationship between inflammatory biomarkers and the prevalence of kidney stones and number of stones passed.

Methods

We conducted a cross-sectional study of adult participants (≥20 years) in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2014. We calculated key inflammatory biomarkers, such as the systemic immune-inflammation index (SII), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and monocyte-lymphocyte ratio (MLR). Multivariate logistic regression analysis was used to determine the effect of inflammatory biomarkers on the prevalence of kidney stones and number of stones passed.

Results

A total of 21,106 participants were included in the final study, and 1,864 patients reported a

SUBMITTER: Mao W 

PROVIDER: S-EPMC7844488 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature