Efficacy and safety of tigecycline for complicated urinary tract infection: a systematic review.

ABSTRACT:

Background

Facing the global threat of emerging resistance to antibiotics, tigecycline, a novel glycylcycline antibiotic, is developed to against multidrug-resistant pathogens, but not recommended for the treatment of complicated urinary tract infection (cUTI). We performed a summary of the literatures to characterize and evaluate the efficacy and safety of tigecycline in patients with cUTI.

Methods

We searched PubMed, EMBASE, Cochrane and Clinical Trials using appropriate syntax to retrieve potential articles up to Jan 2020. General information, pathogen, medication regimen, comorbidities of patients from eligible literatures were recorded. Univariate logistic regression analysis was used to detect the potential factors associated with clinical cure.

Results

Nineteen

SUBMITTER: Liu YX 

PROVIDER: S-EPMC7844507 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature