Serum interleukin 6 and acute urinary retention in elderly men with benign prostatic hyperplasia in China: a cross-sectional study.

ABSTRACT:

Background

While acute urinary retention (AUR) is a severe complication of benign prostatic hyperplasia (BPH), it can also indicate the progression of this common disease in aging men. This study aimed at exploring the possible relationship between serum interleukin 6 (sIL-6) and AUR in BPH patients.

Methods

A cross-sectional study was conducted based on 256 elderly men with BPH in China. The association between the sIL-6 level and the occurrence of AUR was evaluated by univariate and multivariable logistic regressions. The receiver operating characteristic (ROC) curve was utilized to determine the discriminant validity of the sIL-6 level and the optimal cut-off value.

Results

The concentration of sIL-6 was significantly elevated in the AUR group (P<0.001). A positive

SUBMITTER: Wu D 

PROVIDER: S-EPMC7844514 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature