Prognostic value of metabolic tumor volume and total lesion glycolysis on preoperative ¹⁸F-FDG PET/CT in patients with localized primary gastrointestinal stromal tumors.

ABSTRACT:

Background

This study aimed to evaluate the prognostic value of pretreatment ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) in patients with localized primary gastrointestinal stromal tumors (GISTs) and to compare the predictive values of ¹⁸F-FDG PET/CT parameters with those of clinicopathological prognostic factors.

Methods

Sixty-two localized GIST patients who underwent staging with ¹⁸F-FDG PET/CT from January 2007 to December 2013 before surgery were retrospectively enrolled. A volume of interest with a standardized uptake value (SUV) threshold of 2.5 was used to determine the metabolic tumor volume (MTV) and total lesion glycolysis (TLG). These metabolic indices, along with the maximum

SUBMITTER: Hwang SH 

PROVIDER: S-EPMC7844977 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature