Symptomatic subsegmental versus more central pulmonary embolism: Clinical outcomes during anticoagulation.

ABSTRACT:

Background

The optimal therapy of patients with acute subsegmental pulmonary embolism (PE) is controversial.

Methods

We used the RIETE (Registro Informatizado Enfermedad TromboEmbólica) database to compare the rate of symptomatic PE recurrences during anticoagulation in patients with subsegmental, segmental, or more central PEs.

Results

Among 15 963 patients with a first episode of symptomatic PE, 834 (5.2%) had subsegmental PE, 3797 (24%) segmental, and 11 332 (71%) more central PE. Most patients in all subgroups received initial therapy with low-molecular-weight heparin, and then most switched to vitamin K antagonists. Median duration of therapy was 179, 185, and 204 days, respectively. During anticoagulation, 183 patients developed PE recurrences, 131 developed dee

SUBMITTER: Fernandez-Capitan C 

PROVIDER: S-EPMC7845079 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature