Analysis of histology and long noncoding RNAs involved in the rabbit hair follicle density using RNA sequencing.

ABSTRACT:

Background

Hair follicle density influences wool fibre production, which is one of the most important traits of the Wan Strain Angora rabbit. However, molecular mechanisms regulating hair follicle density have remained elusive.

Results

In this study, hair follicle density at different body sites of Wan Strain Angora rabbits with high and low wool production (HWP and LWP) was investigated by histological analysis. Haematoxylin-eosin staining showed a higher hair follicle density in the skin of the HWP rabbits. The long noncoding RNA (lncRNA) profile was investigated by RNA sequencing, and 50 and 38 differentially expressed (DE) lncRNAs and genes, respectively, were screened between the HWP and LWP groups. A gene ontology analysis revealed that phospholipid, lipid metabolic, a

SUBMITTER: Ding H 

PROVIDER: S-EPMC7845105 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature