Association of hot flushes with ghrelin and adipokines in early versus late postmenopausal women.

ABSTRACT:

Objective

Vasomotor flushing (hot flushes) is a common menopausal symptom experienced by most women going through the menopausal transition; flushing continues for a variable period in postmenopause. Primarily due to lack of ovarian estrogen, other biomarkers of hot flushes have not been clearly identified. We examined the relationship of hot flushes with ghrelin and adipokines.

Methods

Baseline data from two clinical trials, the Women's Isoflavone Soy Health (WISH) trial and Early versus Late Intervention Trial of Estrogen (ELITE), were used in this post hoc cross-sectional study. Both WISH and ELITE had similar study designs, inclusion criteria, and data collection processes. Study participants were healthy postmenopausal women not taking estrogen-based hormone therapy, fr

SUBMITTER: Karim R 

PROVIDER: S-EPMC7845756 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature