Radiomics Repeatability Pitfalls in a Scan-Rescan MRI Study of Glioblastoma.

ABSTRACT:

Purpose

To determine the influence of preprocessing on the repeatability and redundancy of radiomics features extracted using a popular open-source radiomics software package in a scan-rescan glioblastoma MRI study.

Materials and methods

In this study, a secondary analysis of T2-weighted fluid-attenuated inversion recovery (FLAIR) and T1-weighted postcontrast images from 48 patients (mean age, 56 years [range, 22-77 years]) diagnosed with glioblastoma were included from two prospective studies (ClinicalTrials.gov NCT00662506 [2009-2011] and NCT00756106 [2008-2011]). All patients underwent two baseline scans 2-6 days apart using identical imaging protocols on 3-T MRI systems. No treatment occurred between scan and rescan, and tumors were essentially unchanged visually. Radiom

SUBMITTER: Hoebel KV 

PROVIDER: S-EPMC7845781 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature