Test-retest reliability of fMRI-measured brain activity during decision making under risk.

ABSTRACT: Neural correlates of decision making under risk are being increasingly utilized as biomarkers of risk for substance abuse and other psychiatric disorders, treatment outcomes, and brain development. This research relies on the basic assumption that fMRI measures of decision making represent stable, trait-like individual differences. However, reliability needs to be established for each individual construct. Here we assessed long-term test-retest reliability (TRR) of regional brain activations related to decision making under risk using the Balloon Analogue Risk Taking task (BART) and identified regions with good TRRs and familial influences, an important prerequisite for the use of fMRI measures in genetic studies. A secondary goal was to examine the factors potentially affecting fMRI TRRs

SUBMITTER: Korucuoglu O 

PROVIDER: S-EPMC7846028 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature