Preoperative transcranial magnetic stimulation for picture naming is reliable in mapping segments of the arcuate fasciculus.

ABSTRACT: In preoperative planning for neurosurgery, both anatomical (diffusion imaging tractography) and functional tools (MR-navigated transcranial magnetic stimulation) are increasingly used to identify and preserve eloquent language structures specific to individuals. Using these tools in healthy adults shows that speech production errors occur mainly in perisylvian cortical sites that correspond to subject-specific terminations of the major language pathway, the arcuate fasciculus. It is not clear whether this correspondence remains in oncological patients with altered tissue. We studied a heterogeneous cohort of 30 patients (fourteen male, mean age 44), undergoing a first or second surgery for a left hemisphere brain tumour in a language-eloquent region, to test whether speech production error

SUBMITTER: Giampiccolo D 

PROVIDER: S-EPMC7846168 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature