Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries.

ABSTRACT:

Background

80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality.

Methods

This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models o

SUBMITTER: GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery 

PROVIDER: S-EPMC7846817 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature