Non-local means based Rician noise filtering for diffusion tensor and kurtosis imaging in human brain and spinal cord.

ABSTRACT:

Background

To investigate the effect of using a Rician nonlocal means (NLM) filter on quantification of diffusion tensor (DT)- and diffusion kurtosis (DK)-derived metrics in various anatomical regions of the human brain and the spinal cord, when combined with a constrained linear least squares (CLLS) approach.

Methods

Prospective brain data from 9 healthy subjects and retrospective spinal cord data from 5 healthy subjects from a 3 T MRI scanner were included in the study. Prior to tensor estimation, registered diffusion weighted images were denoised by an optimized blockwise NLM filter with CLLS. Mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), mean diffusivity (MD), radial diffusivity (RD), axial diffusivity (AD) and fractional anisotropy (FA), were determined

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC7847150 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature