The Malmo Offspring Study (MOS): design, methods and first results.

ABSTRACT: As cardio metabolic disease manifestations tend to cluster in families there is a need to better understand the underlying mechanisms in order to further develop preventive strategies. In fact, genetic markers used in genetic risk scores, important as they are, will not be able alone to explain these family clusters. Therefore, the search goes on for the so called missing heritability to better explain these associations. Shared lifestyle and social conditions in families, but also early life influences may be of importance. Gene-environmental interactions should be explored. In recent years interest has grown for the role of diet-microbiota associations, as microbiota patterns may be shared by family members. In the Malmö Offspring Study that started in 2013, we have so far been able to e

SUBMITTER: Brunkwall L 

PROVIDER: S-EPMC7847466 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature