Are there subgroups of chronic fatigue syndrome? An exploratory cluster analysis of biological markers.

ABSTRACT:

Background

Chronic fatigue syndrome (CFS) is defined according to subjective symptoms only, and several conflicting case definition exist. Previous research has discovered certain biological alterations. The aim of the present study was to explore possible subgroups based on biological markers within a widely defined cohort of adolescent CFS patients and investigate to what extent eventual subgroups are associated with other variables.

Methods

The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial (NorCAPITAL) has previously performed detailed investigation of immunological, autonomic, neuroendocrine, cognitive and sensory processing functions in an adolescent group of CFS patients recruited according to wide diagnostic criteri

SUBMITTER: Asprusten TT 

PROVIDER: S-EPMC7847574 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature