Identifying daily changes in circRNAs and circRNA-associated-ceRNA networks in the rat pineal gland.

ABSTRACT: Circular RNAs (circRNAs) are a new class of covalently closed circular RNA molecules that are involved in many biological processes. However, information about circRNAs in the pineal gland, particularly that of rats, is limited. To establish resources for the study of the rat pineal gland, we performed transcriptome analysis of the pineal glands during the day and night. In this study, 1413 circRNAs and 1989 miRNAs were identified in the pineal gland of rats during the night and day using the Illumina platform. Forty differentially expressed circRNAs and 93 differentially expressed miRNAs were obtained, among which 20 circRNAs and 37 miRNAs were significantly upregulated during the day and 20 circRNAs and 56 miRNAs were significantly upregulated during the night. As circRNAs have been repo

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC7847611 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature