Hydrolysates from bee pollen could induced apoptosis in human bronchogenic carcinoma cells (ChaGo-K-1).

ABSTRACT: In order to examine bee pollen hydrolysates to assess their anticancer and antioxidant properties, hydrolysis of bee pollen was first performed using three different commercially available enzymes: Alcalase^®, Neutrase^®, and Flavourzyme^®. The study used DPPH and ABTS assay to evaluate the antioxidant properties of the hydrolysates obtained from bee pollen. All of the tested hydrolysates demonstrated antioxidant activity, while hydrolysate based on Alcalase^® offered a high value for IC₅₀ and was therefore chosen for further separation into five sub-fractions via ultrafiltration. The greatest antioxidant activity was presented by the MW < 0.65 kDa fraction, which achieved an IC₅₀ value of 0.39 ± 0.01 µg/mL in the DPPH assay and

SUBMITTER: Saisavoey T 

PROVIDER: S-EPMC7847929 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature