Phylogenomic fingerprinting of tempo and functions of horizontal gene transfer within ochrophytes.

ABSTRACT: Horizontal gene transfer (HGT) is an important source of novelty in eukaryotic genomes. This is particularly true for the ochrophytes, a diverse and important group of algae. Previous studies have shown that ochrophytes possess a mosaic of genes derived from bacteria and eukaryotic algae, acquired through chloroplast endosymbiosis and from HGTs, although understanding of the time points and mechanisms underpinning these transfers has been restricted by the depth of taxonomic sampling possible. We harness an expanded set of ochrophyte sequence libraries, alongside automated and manual phylogenetic annotation, in silico modeling, and experimental techniques, to assess the frequency and functions of HGT across this lineage. Through manual annotation of thousands of single-gene trees, we ident

SUBMITTER: Dorrell RG 

PROVIDER: S-EPMC7848541 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature