Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling.

ABSTRACT: Bacteria have evolved a variety of signal transduction mechanisms that generate different outputs in response to external stimuli. Chemosensory pathways are widespread in bacteria and are among the most complex signaling mechanisms, requiring the participation of at least six proteins. These pathways mediate flagellar chemotaxis, in addition to controlling alternative functions such as second messenger levels or twitching motility. The human pathogen Pseudomonas aeruginosa has four different chemosensory pathways that carry out different functions and are stimulated by signal binding to 26 chemoreceptors. Recent research employing a diverse range of experimental approaches has advanced enormously our knowledge on these four pathways, establishing P. aeruginosa as a primary model organism i

SUBMITTER: Matilla MA 

PROVIDER: S-EPMC7849354 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature