Thermal stress accelerates Arabidopsis thaliana mutation rate.

ABSTRACT: Mutations are the source of both genetic diversity and mutational load. However, the effects of increasing environmental temperature on plant mutation rates and relative impact on specific mutational classes (e.g., insertion/deletion [indel] vs. single nucleotide variant [SNV]) are unknown. This topic is important because of the poorly defined effects of anthropogenic global temperature rise on biological systems. Here, we show the impact of temperature increase on Arabidopsis thaliana mutation, studying whole genome profiles of mutation accumulation (MA) lineages grown for 11 successive generations at 29°C. Whereas growth of A. thaliana at standard temperature (ST; 23°C) is associated with a mutation rate of 7 × 10^-9 base substitutions per site per generation, gro

SUBMITTER: Belfield EJ 

PROVIDER: S-EPMC7849391 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature