Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population.

ABSTRACT:

Objective

Staphylococcus aureus is a major human pathogen, and nasal carriers have an increased risk for infection and disease. The exploration of host determinants for nasal carriage is relevant to decrease infection burden. Former studies demonstrate lower carriage prevalence in women and among users of progestin-only contraceptives. The aim of this study was to investigate the possible associations between circulating sex-steroid hormones and nasal carriage of Staphylococcus aureus in a general population.

Methods

In the population-based sixth Tromsø study (2007-2008) nurses collected nasal swab samples from 724 women aged 30-87 not using any exogenous hormones, and 700 of the women had a repeated nasal swab taken (median interval 28 days). We analysed a panel of serum se

SUBMITTER: Stensen DB 

PROVIDER: S-EPMC7849480 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature