Effects of coconut water on blood sugar and retina of rats with diabetes.

ABSTRACT:

Background

This study aimed to evaluate the effects of coconut water on the general condition (fasting blood sugar and body weight) and retina of diabetic rats.

Methods

Forty-eight Sprague-Dawley male rats were divided into normal controls (NC), diabetes mellitus (DM), diabetes+coconut water (DM+CW), and diabetes+glibenclamide (DM+Gli) groups. After 4 weeks of normal feeding, coconut water was given to group III-DM+CW and 0.6 mg/kg glibenclamide to group IV-DM+Gli. The blood sugar, body weight, total retinal thickness, pathological changes, and VEGF expression in the retina were analyzed at different time points.

Results

The fasting blood sugar was 4-6 mmol/L in group I-NC and continuously increased in group II-DM, whereas gradually decreased after the 4th experiment

SUBMITTER: Dai Y 

PROVIDER: S-EPMC7849505 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature