Association between sleep structure and amnesic mild cognitive impairment in patients with insomnia disorder: a case-control study.

ABSTRACT:

Study objectives

To examine the association between sleep structure and amnesic mild cognitive impairment (aMCI) in patients with insomnia disorder.

Methods

A total of 256 patients with insomnia disorder were diagnosed by neurologists, 45 of whom were diagnosed with aMCI according to the Petersen criteria, and 45 participants with intact cognition were chosen as controls matched for age and education. A case-control study was conducted to compare sleep structure between aMCI and control patients with insomnia disorder. We evaluated self-reported sleep problems by the Insomnia Severity Index and objective sleep features by polysomnography. Logistic regression models were used to estimate the associations between sleep parameters and aMCI in patients with insomnia disorder.

SUBMITTER: Zhang L 

PROVIDER: S-EPMC7849649 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature