Human white-fat thermogenesis: Experimental and meta-analytic findings.

ABSTRACT: White adipose tissue (WAT) thermogenic activity may play a role in whole-body energy balance and two of its main regulators are thought to be environmental temperature (T_env) and exercise. Low T_env may increase uncoupling protein one (UCP1; the main biomarker of thermogenic activity) in WAT to regulate body temperature. On the other hand, exercise may stimulate UCP1 in WAT, which is thought to alter body weight regulation. However, our understanding of the roles (if any) of T_env and exercise in WAT thermogenic activity remains incomplete. Our aim was to examine the impacts of low T_env and exercise on WAT thermogenic activity, which may alter energy homeostasis and body weight regulation. We conducted a series of four experimental studies, support

SUBMITTER: Dinas PC 

PROVIDER: S-EPMC7849687 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature