Frequency and severity of autonomic symptoms in idiopathic hypersomnia.

ABSTRACT:

Study objectives

We aimed to quantify the symptoms of autonomic nervous system dysfunction in a large online cohort of patients with idiopathic hypersomnia, and to determine how the severity of these symptoms interacts with sleepiness, fatigue, and quality of life.

Methods

One hundred thirty-eight patients with idiopathic hypersomnia and 81 age- and sex-matched controls were recruited through the website of the Hypersomnia Foundation, a US-based patient advocacy group. Twenty-four patients with confirmed idiopathic hypersomnia were selected by the study investigators as a comparison group. All participants completed a battery of online sleep, autonomic, and quality of life questionnaires including the composite autonomic symptom score-31 (COMPASS-31).

Results

Online a

SUBMITTER: Miglis MG 

PROVIDER: S-EPMC7849804 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature