Randomised controlled trial protocol for the PROTECT-CS Study: PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery.

ABSTRACT:

Introduction

In the past 20 years, the increasing burden of heart disease in an ageing population has resulted in cardiac surgery (CS) being offered to more frail and older patients with multiple comorbidities. Frailty and malnutrition are key geriatric syndromes that impact postoperative outcomes, including morbidity, mortality and prolonged hospital length of stay. Enhanced recovery protocols (ERPs), such as prehabilitation, have been associated with a reduction in complications after CS in vulnerable patients. The use of nutritional ERPs may enhance short-term and long-term recovery and mitigate frailty progression while improving patient-reported outcomes.

Methods and analysis

This trial is a two-centre, double-blinded, placebo, randomised controlled trial with blinded e

SUBMITTER: Rose AV 

PROVIDER: S-EPMC7849881 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature