Haematological abnormalities in new-onset rheumatoid arthritis and risk of common infections: a population-based study.

ABSTRACT:

Objectives

To describe the prevalence of haematological abnormalities in individuals with RA at the point of diagnosis in primary care and the associations between haematological abnormalities, vaccinations and subsequent risk of common infections.

Methods

We studied 6591 individuals with newly diagnosed RA between 2004 and 2016 inclusive using the UK Royal College of General Practitioners Research and Surveillance Centre primary care database. The prevalence of haematological abnormalities at diagnosis (anaemia, neutropenia and lymphopenia) was established. Cox proportional hazards models were used to evaluate the association between each haematological abnormality and time to common infections and the influence of vaccination status (influenza and pneumococcal vaccine) on

SUBMITTER: Nikiphorou E 

PROVIDER: S-EPMC7849938 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature