Fecal Bacteria as Biomarkers for Predicting Food Intake in Healthy Adults.

ABSTRACT:

Background

Diet affects the human gastrointestinal microbiota. Blood and urine samples have been used to determine nutritional biomarkers. However, there is a dearth of knowledge on the utility of fecal biomarkers, including microbes, as biomarkers of food intake.

Objectives

This study aimed to identify a compact set of fecal microbial biomarkers of food intake with high predictive accuracy.

Methods

Data were aggregated from 5 controlled feeding studies in metabolically healthy adults (n = 285; 21-75 y; BMI 19-59 kg/m2; 340 data observations) that studied the impact of specific foods (almonds, avocados, broccoli, walnuts, and whole-grain barley and whole-grain oats) on the human gastrointestinal microbiota. Fecal DNA was sequenced using 16S ribosomal RNA gene sequenci

SUBMITTER: Shinn LM 

PROVIDER: S-EPMC7849973 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature