Whole-Genome Resequencing Reveals Adaptation Prior to the Divergence of Buffalo Subspecies.

ABSTRACT: The application of high-throughput genotyping or sequencing data helps us to understand the genomic response to natural and artificial selection. In this study, we scanned the genomes of five indigenous buffalo populations belong to three recognized breeds, adapted to different geographical and agro-ecological zones in Iran, to unravel the extent of genomic diversity and to localize genomic regions and genes underwent past selection. A total of 46 river buffalo whole genomes, from West and East Azerbaijan, Gilan, Mazandaran, and Khuzestan provinces, were resequenced. Our sequencing data reached to a coverage above 99% of the river buffalo reference genome and an average read depth around 9.2× per sample. We identified 20.55 million SNPs, including 63,097 missense, 707 stop-gain, and 159 st

SUBMITTER: Rafiepour M 

PROVIDER: S-EPMC7850101 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature