Risk factors associated with Pneumocystis jirovecii pneumonia in juvenile myositis in North America.

ABSTRACT:

Objectives

Pneumocystis jirovecii pneumonia (PJP) is associated with significant morbidity and mortality in adult myositis patients; however, there are few studies examining PJP in juvenile myositis [juvenile idiopathic inflammatory myopathy (JIIM)]. The purpose of this study was to determine the risk factors and clinical phenotypes associated with PJP in JIIM.

Methods

An research electronic data capture (REDCap) questionnaire regarding myositis features, disease course, medications and PJP infection characteristics was completed by treating physicians for 13 JIIM patients who developed PJP (PJP+) from the USA and Canada. Myositis features and medications were compared with 147 JIIM patients without PJP (PJP-) from similar geographic regions who enrolled in National Institut

SUBMITTER: Sabbagh SE 

PROVIDER: S-EPMC7850515 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature