Outcomes Associated With Medications for Opioid Use Disorder Among Persons Hospitalized for Infective Endocarditis.

ABSTRACT:

Background

Endocarditis, once predominately found in older adults, is increasingly common among younger persons who inject drugs. Untreated opioid use disorder (OUD) complicates endocarditis management. We aimed to determine if rates of overdose and rehospitalization differ between persons with OUD with endocarditis who are initiated on medications for OUD (MOUDs) within 30 days of hospital discharge and those who are not.

Methods

We performed a retrospective cohort study using a large commercial health insurance claims database of persons ≥18 years between July 1, 2010, and June 30, 2016. Primary outcomes included opioid-related overdoses and 1-year all-cause rehospitalization. We calculated incidence rates for the primary outcomes and developed Cox hazards models to predic

SUBMITTER: Barocas JA 

PROVIDER: S-EPMC7850516 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature