How to Choose Target Facilities in a Region to Implement Carbapenem-resistant Enterobacteriaceae Control Measures.

ABSTRACT:

Background

When trying to control regional spread of antibiotic-resistant pathogens such as carbapenem-resistant Enterobacteriaceae (CRE), decision makers must choose the highest-yield facilities to target for interventions. The question is, with limited resources, how best to choose these facilities.

Methods

Using our Regional Healthcare Ecosystem Analyst-generated agent-based model of all Chicago metropolitan area inpatient facilities, we simulated the spread of CRE and different ways of choosing facilities to apply a prevention bundle (screening, chlorhexidine gluconate bathing, hand hygiene, geographic separation, and patient registry) to a resource-limited 1686 inpatient beds.

Results

Randomly selecting facilities did not impact prevalence, but averted 620 new ca

SUBMITTER: Lee BY 

PROVIDER: S-EPMC7850552 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature