Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations.

ABSTRACT: Meiotic recombination is a critical process that ensures proper segregation of chromosome homologs through DNA double-strand break repair mechanisms. Rates of recombination are highly variable among various taxa, within species, and within genomes with far-reaching evolutionary and genomic consequences. The genetic basis of recombination rate variation is therefore crucial in the study of evolutionary biology but remains poorly understood. In this study, we took advantage of a set of experimental temperature-evolved populations of Drosophila melanogaster with heritable differences in recombination rates depending on the temperature regime in which they evolved. We performed whole-genome sequencing and identified several chromosomal regions that appear to be divergent depending on temperatu

SUBMITTER: Winbush A 

PROVIDER: S-EPMC7851596 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature