Trends over time in drug administration during pediatric in-hospital cardiac arrest in the United States.

ABSTRACT:

Aims

To describe trends in pediatric in-hospital cardiac arrest drug administration and to assess temporal associations of the Pediatric Advanced Life Support (PALS) guideline changes with drug usage.

Methods

Pediatric patients <18 years old with in-hospital cardiac arrest recorded in the American Heart Association Get With The Guidelines-Resuscitation database between 2002 and 2018 were included. The annual adjusted odds of receiving each intra-arrest medication was determined. The association between changes in the PALS Guidelines and medication use over time was assessed interrupted time series analyses.

Results

A total of 6107 patients were analyzed. The adjusted odds of receiving lidocaine (0.33; 95% CI, 0.18, 0.61; p < 0.001), atropine (0.19; 95% CI 0.12, 0.30;

SUBMITTER: Ross CE 

PROVIDER: S-EPMC7851749 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature