A high-protein total diet replacement increases energy expenditure and leads to negative fat balance in healthy, normal-weight adults.

ABSTRACT:

Background

High-protein diets and total diet replacements are becoming increasingly popular for weight loss; however, further research is needed to elucidate their impact on the mechanisms involved in weight regulation.

Objective

The aim of this inpatient metabolic balance study was to compare the impact of a high-protein total diet replacement (HP-TDR) versus a control diet (CON) on select components of energy metabolism in healthy adults of both sexes.

Methods

The acute intervention was a randomized, controlled, crossover design with participants allocated to 2 isocaloric arms: 1) HP-TDR: 35% carbohydrate, 40% protein, and 25% fat achieved through a nutritional supplement; 2) CON: 55% carbohydrate, 15% protein, and 30% fat. Participants received the prescribed diets

SUBMITTER: Oliveira CLP 

PROVIDER: S-EPMC7851826 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature