Performance of the coronary calcium score in an outpatient chest pain clinic and strategies for risk stratification.

ABSTRACT:

Background

Coronary artery calcium score (CAC) is an objective marker of atherosclerosis. The primary aim is to assess CAC as a risk classifier in stable coronary artery disease (CAD).

Hypothesis

CAC improves CAD risk prediction, compared to conventional risk scoring, even in the absence of cardiovascular risk factor inputs.

Methods

Outpatients presenting to a cardiology clinic (n = 3518) were divided into two cohorts: derivation (n = 2344 patients) and validation (n = 1174 patients). Adding logarithmic transformation of CAC, we built two logistic regression models: Model 1 with chest pain history and risk factors and Model 2 including chest pain history only without risk factors simulating patients with undiagnosed comorbidities. The CAD I Consortium Score (CCS) was

SUBMITTER: Huang W 

PROVIDER: S-EPMC7852173 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature