Foot-and-mouth disease virus infection in the domestic dog (Canis lupus familiaris), Iran.

ABSTRACT:

Background

Foot-and-mouth disease (FMD) is a highly infectious viral disease, recognised to affect animals in the order Artiodactyla. The disease is rarely fatal in adult animals, however high mortality is associated with neonatal and juvenile infection.

Case presentation

Five puppies died after being fed lamb carcases, the lambs having died during an outbreak of FMD in Iran. Following a post-mortem examination, cardiac tissue from one of the dead puppies was subjected to virus isolation, antigen ELISA, real-time RT-PCR, sequencing and confocal microscopy to assess the presence and characteristics of any FMD virus. The virological and microscopic examination of the cardiac tissue provided evidence of FMD virus replication in the canine heart.

Conclusions

The data gene

SUBMITTER: Waters RA 

PROVIDER: S-EPMC7852191 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature