Insecticidal efficacy of afoxolaner against bedbugs, Cimex lectularius, when administered orally to dogs.

ABSTRACT: The objective of this experimental study was to assess the insecticidal efficacy of afoxolaner (NexGard^®) against bedbugs (Cimex lectularius) on dogs. For each challenge, 20 bedbugs were placed in two chambers positioned in contact to the dog's skin for 15 min, after which live fed parasites were counted and incubated for survival evaluations. On Day 0, 7 dogs assigned to the treated group were administered afoxolaner orally at the registered dose. All 14 dogs were challenged on Days 1, 7, 14, 21 and 28, and the collected live fed C. lectularius incubated for 72 h (Day 1), and 72 h and 96 h (Days 7, 14, 21 and 28) for survival evaluation. The percent feeding in the control group ranged from 95% to 98.6% and the percent of live fed bedbugs at 96 h ranged from 99.3% to 100% in the

SUBMITTER: Beugnet F 

PROVIDER: S-EPMC7852378 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature