Association of post-diagnostic use of cholera vaccine with survival outcome in breast cancer patients.

ABSTRACT:

Background

Expensive cancer treatment calls for alternative ways such as drug repurposing to develop effective drugs. The aim of this study was to analyse the effect of post-diagnostic use of cholera vaccine on survival outcome in breast cancer patients.

Methods

Cancer diagnosis and cholera vaccination were obtained by linkage of several Swedish national registries. One vaccinated patient was matched with maximum two unvaccinated individuals based on demographic, clinical and socioeconomic factors. We performed proportional Cox regression model to analyse the differences in overall and disease-specific survivals between the matched patients.

Results

In total, 617 patients received cholera vaccine after breast cancer diagnosis. The median (interquartile range) time fro

SUBMITTER: Zheng G 

PROVIDER: S-EPMC7852596 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature