Conventional Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Disorders: A Meta-Analysis.

ABSTRACT:

Background

Numerous conventional magnetic resonance imaging (cMRI) parameters were previously found to differentiate parkinsonian disorders with statistical significance, but effect size has not been considered.

Objectives

To quantify effect size of previously identified cMRI parameters that differentiated parkinsonian disorders with statistical significance.

Method

A PubMed search limited to studies assessing cMRI parameters in at least 2 of Parkinson's disease, progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration/syndrome were selected. Either Cohen's d or positive and negative likelihood (LR+/-) as well as diagnostic odds ratios (DORs) were calculated as appropriate. cMRI parameter was considered useful if Cohen's d > 1.94 (<20% ov

SUBMITTER: Lee W 

PROVIDER: S-EPMC7853196 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature